The Iglesia de Santo Domingo sits quietly in Granada's Realejo neighborhood, watching over a charming plaza where a statue of Fray Luis de Granada stands as a reminder of the monastery's scholarly past. I've walked through this square many times, and there's something compelling about how this church anchors the entire area with its mix of architectural styles.

Construction began in 1512 in Gothic style, though you can see how different periods left their mark. The Renaissance, Baroque, and even contemporary additions create an eclectic building that somehow works beautifully together. What strikes you first is the unusual stone portico with three semi-circular arches supported by columns. Look closely at the spandrels and you'll spot the initials "F" and "Y" – Fernando and Ysabel, the Catholic Monarchs who funded this project.

The coats of arms tell quite a story too. One side displays the Catholic Monarchs' eagle of Saint John, while the other shows Emperor Charles's double-headed eagle with the famous motto "Tanto monta" in the center. Above the entrance portico, there's an elegant window framed by decorative arches with carved victories that catches the afternoon light perfectly.

Inside, the single wide nave feels surprisingly spacious, with five chapels along each side and Gothic ribbed vaults overhead. The marble tabernacle from 1699 commands attention in the presbytery, but the real showstopper is the baroque altarpiece housing the Virgen del Rosario Coronada, Granada's co-patron saint. Completed by Blas Antonio Moreno after 1759, it's an exuberant display of angels, cherubs, and baroque elements that seems to dance up the walls.

This church plays a significant role during Granada's Holy Week, hosting several important brotherhoods. The Hermandad de la Santa Cena processes on Palm Sunday, while the Humildad brotherhood – locally known as "La Cañilla" – makes three appearances throughout the week. The atmosphere during these processions transforms the entire neighborhood.

If you're exploring Granada thoroughly, an audio guide can help decode the layers of history and artistic details that might otherwise go unnoticed. The church opens daily, respecting liturgical celebrations, and fits naturally into any walk through the historic Realejo district.